OSDrC : A Revolution in Drug Formulation Technology

Conventional dry-coating method can cause problems like non-core, double-core, off-center, inlay, and cooking, caused by the core tablet supply system. Hence, dry coating is not as widely used as normal tablets. One-step dry-coating (OSDrC) technology is an innovative one to solve these problems. OSDrC technology, which does not require a separate manufacturing process for the core, can even use powders with poor compressibility as the core matrix. This system can be assembled onto the turn table of a rotary tableting machine, and can make a dry-coated tablet in a single turn. This manufacturing method does not require the preparation of the core tablets beforehand, allowing the dry-coating to be made in one process. Compared with the controlled release tablet using membrane by the conventional film coating tablets, OSDrC which can be made by OSDrC-system are useful in the simple manufacturing method, the low manufacturing cost and the easy process management. In general, OSDrC could be a platform for full-range of controlled release tablets. Under this scenario, an understanding of this novel technology could be beneficial for the readers. This mini-review aims to highlight the benefits and mechanism of operation of OSDrC systems.